DNA/RNA - Protein Synthesis
This kit demystifies the DNA/RNA connection in protein synthesis. Using individualized student worksheets and plastic, color-coded components, students first build a DNA molecule, replicate it, and use half of the ladder
to build mRNA (messenger RNA). Nucleotides of RNA are first produced following these step-by-step directions, making the chemistry easily understood. Transcription in the nucleus and the movement of the mRNA molecule are simulated by placing it on a model ribosome. At this time, translation is simulated by matching the mRNA and its codons to the tRNA (transfer RNA) and its anticodons. The amino acids bond to form a protein molecule. Students experience how the information stored in DNA is expressed as a finished protein. Students conclude by disconnecting the protein chain from the tRNA and the tRNAs from the mRNA, showing their availability to continue the process. Complete for 24 students working in pairs.